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Grape Seed Extract and Blood Thinners: What the Cautions Rest On
Grape seed extract and blood thinners should be checked with a pharmacist before you combine them. Trials studied 100 to 300 mg a day. The Reviralis label lists grape seed extract 10th in a 661 mg blend, at most 66.1 mg per serving, amount unprinted. Several other names in that blend carry bleeding notes too.
Written by the Goreviralis label deskUpdated · 5 min read

What did grape seed extract trials measure?
Mostly short-term blood pressure and general tolerance. NCCIH says grape seed extract has been studied at 100 to 300 mg a day and is generally well tolerated in the short term (NCCIH, Grape Seed Extract).
"Well tolerated short term" is not the same as "checked against warfarin." A trial that enrolls healthy volunteers tells a person on a blood thinner very little. The people with the most to lose from a bleeding interaction are the people usually left out of the study.
How much grape seed extract is in Reviralis?
The label does not say. Grape seed extract is 10th of 18 names in a 661 mg blend, so it can hold at most 66.1 mg per two-capsule serving.
US rules list blend members from most to least by weight (21 CFR 101.36). The 10th name holds no more than 661 divided by 10. At the ceiling it still sits under the 100 mg low end of the studied range. A lower real figure would sit further under.
| Measure | Amount |
|---|---|
| Studied daily range (NCCIH) | 100 to 300 mg |
| Reviralis blend position | 10th of 18 |
| Printed amount | Not printed |
| Ceiling per serving | At most 66.1 mg |
Do other Reviralis ingredients also matter for blood thinners?
Yes. Grape seed is not the only name with a bleeding note, and notes from different names can add up.
- Vitamin E is 27 mg on the label; high doses may increase bleeding risk, including with anticoagulants (NIH ODS, Vitamin E).
- DHA is in the blend; high doses of omega-3 may prolong bleeding (NIH ODS, Omega-3 Fatty Acids).
- Bilberry fruit extract may add to blood thinners (MSK About Herbs, Bilberry Fruit).
The label asks people on prescription medicine, "particularly antidepressants, blood thinners or medicine affecting the nervous or cardiovascular system," to consult a provider before use.

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See packsWhat should you do if you take a blood thinner?
Do not start, stop or swap anything on your own. Take the bottle to the person who manages your blood thinner and ask.
"This capsule lists grape seed extract, bilberry, DHA and vitamin E. Do any of them matter with my blood thinner, and should my blood tests change?"
Keep taking every prescribed medicine, including an antiviral, as directed. Call 911 for bleeding that will not stop, black or bloody stools, vomiting blood, a sudden severe headache or confusion.
Where can you read more before deciding?
Start with the pages that cover the blend and medicine questions in full.
Read the medicine check page and the blend math. For the wider topic, see supplements and warfarin. No source tested Reviralis, and none links grape seed to herpes.
FAQ01
Reviralis questions people ask
Can you take grape seed extract with warfarin?
Ask the prescriber first. Grape seed extract may add to bleeding effects, and warfarin dosing is sensitive. A pharmacist can check your whole list and tell you whether extra blood tests are needed.
How much grape seed extract is in Reviralis?
The label does not print it. Grape seed extract is 10th of 18 names in a 661 mg blend, so it holds at most 66.1 mg per serving. The real amount may be lower.
What dose of grape seed extract was studied?
NCCIH reports 100 to 300 mg a day in studies, with good short-term tolerance. The Reviralis ceiling of 66.1 mg is under that range.
Does grape seed extract affect blood pressure?
Some trials looked at it. Anyone on blood pressure medicine should ask before adding it, since effects can stack.
Does Reviralis work with aspirin?
No source tested that. Aspirin affects bleeding, and several Reviralis names have bleeding notes, so ask your pharmacist before combining them.
Who wrote this02
Written and reviewed by
Pages built from the label, the sales page and linked NIH, CDC, FDA, FTC, Mayo Clinic and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is the information site for a U.S. stocking partner for Reviralis. It is not the manufacturer or the distributor named on the label. We earn money when you buy through our order links.
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